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Sexual function outcomes of radiation and androgen deprivation therapy for localized prostate cancer in men with good baseline function.

Stephen B WilliamsChristopher J D WallisAmy N LuckenbaughHeather L HuelsterZhiguo ZhaoKaren E HoffmanLi-Ching HuangTatsuki KoyamaRalph ConwillMichael GoodmanAnn S HamiltonXiao-Cheng WuLisa E PaddockAntoinette StroupMatthew R CooperbergMia HashibeBrock B O' NeilSherrie H KaplanSheldon GreenfieldDavid F PensonDaniel A Barocas
Published in: Prostate cancer and prostatic diseases (2021)
Androgen deprivation therapy plus radiation is associated with worse sexual function through 3-years follow-up in men with high-risk prostate cancer compared to radiation alone. The addition of androgen deprivation therapy in the treatment of intermediate-risk disease does not appear to result in worse sexual function at 3 or 5-year follow-up compared to radiation alone.
Keyphrases
  • prostate cancer
  • radical prostatectomy
  • radiation induced
  • middle aged
  • stem cells
  • metabolic syndrome
  • insulin resistance