Usefulness of r Ana o 3 assessment before oral food challenge to pistachio.

Cashew and pistachio both belong to the Anarcardiacae family. Cashew and pistachio allergies may cause severe symptoms such as anaphylaxis with a very low eliciting dose1,2 . The cashew 2S albumin r Ana o 3 is the only singleplex component-resolved diagnosis immunoassay currently available in clinical practice3-5 . Its structural similarity with the pistachio 2S albumin may explain the cross-reactivity between cashew and pistachio6 . The main objective of this study was to assess the performance of specific IgE to r Ana o 3 for the diagnosis of pistachio allergy.