Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy.

Kristen N HaggertyShannon C EshelmanLauren A SextonEmmanuel FrimpongLeah M RogersMelina A Agosto Michael A Robichaux

Published in: bioRxiv : the preprint server for biology (2023)

Photoreceptor cells of the retina are maintained through a complex protein trafficking network. This study applies quantitative super-resolution microscopy to uncover localization details about the trafficking of the essential visual pigment rhodopsin in the inner segment region of rod photoreceptors.

Keyphrases

high resolution
single molecule
induced apoptosis
high speed
optical coherence tomography
mass spectrometry
cell cycle arrest
diabetic retinopathy
endoplasmic reticulum stress
signaling pathway
cell proliferation
oxidative stress
amino acid
small molecule