TLR4 polymorphism and haplotype are associated with obesity and lipid profile in young population: a pilot study.

R Rodríguez-GarcíaM Vazquez-VillamarG Aparicio-OzoresI Parra-RojasR B Radilla-VázquezNatividad Castro-Alarcón

Published in: Journal of endocrinological investigation (2022)

The heterozygous genotype of the SNPs - 2081 G > A, 896 A > G and 1196 C > T of the TLR4 gene was associated with altered lipid profile and development of obesity in young university students of Guerrero State, Mexico.

Keyphrases

insulin resistance
metabolic syndrome
toll like receptor
weight loss
inflammatory response
high fat diet induced
type diabetes
genome wide
weight gain
immune response
middle aged
early onset
nuclear factor
dna methylation
gene expression
genome wide identification