Effect of the combination of diuretics, renin-angiotensin-aldosterone system inhibitors, and non-steroidal anti-inflammatory drugs or metamizole (triple whammy) on hospitalisation due to acute kidney injury: a nested case-control study.
Dulce Maria CalvoLuis Carlos SaizLeire LeacheMaria Concepción CelayaMarta Gutiérrez-ValenciaAlvaro AlonsoJuan ErvitiNatalia AlzuetaAmaya EcheverríaJavier GarjónCarmen FontelaLorea SanzMaria Teresa AcínMaria Loreto FernándezNerea GómezPublished in: Pharmacoepidemiology and drug safety (2023)
Vigilance should be increased when diuretics, RAAS inhibitors, and NSAIDs or metamizole are used concomitantly, especially in patients at risk such as elderly patients.