Pharmacokinetics and Biodistribution of Thymoquinone-loaded Nanostructured Lipid Carrier After Oral and Intravenous Administration into Rats.
Fatin Hannani Zakarial AnsarSaiful Yazan LatifahWan Hamirul Bahrin Wan KamalKhei Choong KhongYen NgJia Ning FoongBanulata GopalsamyWei Keat NgChee Wun HowYong Sze OngAbdullah RasedeeMohd Yusmaidie AzizPublished in: International journal of nanomedicine (2020)
TQ-NLC had better absorption when administered intravenously compared to oral administration. However, oral administration showed greater bioavailability compared to the intravenous route. This study provides the pharmacokinetics and biodistribution profile of TQ-NLC in vivo which is useful to assist researchers in clinical use.