Delay in treatment initiation and treatment outcomes among adult patients with multidrug-resistant tuberculosis at Yangon Regional Tuberculosis Centre, Myanmar: A retrospective study.
Ye Minn HtunTin Mi Mi KhaingNay Myo AungYin YinZaw MyintSi Thu AungNgamphol SoonthornworasiriUdomsak SilachamroonYuthichai KasetjaroenJaranit KaewkungwalPublished in: PloS one (2018)
Post-diagnosis delays in the initiation of treatment among MDR-TB patients were significantly long. The study results showed that inadequate MDR-TB treatment initiation center, centralization of treatment initiation, limitation of human resources, were health-system factors delaying timely treatment initiation and implementation of an effective TB-control program. Our findings highlight the need for immediate interventions to reduce treatment delay and improve treatment outcomes, including scaling up diagnostic capacity with Xpert MTB/RIF at township level, expansion of decentralized MDR-TB treatment initiation centers, ensuring a productive health workforce comprising trained health personnel, and providing health education and treatment-adherence counseling to patients and family members.
Keyphrases
- multidrug resistant
- mycobacterium tuberculosis
- public health
- healthcare
- primary care
- emergency department
- risk assessment
- type diabetes
- physical activity
- end stage renal disease
- escherichia coli
- ejection fraction
- adipose tissue
- pulmonary tuberculosis
- drug resistant
- cystic fibrosis
- social media
- hepatitis c virus
- body composition
- human immunodeficiency virus
- health information
- men who have sex with men
- human health
- patient reported outcomes
- antiretroviral therapy
- patient reported