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Assessment of lung deformation in patients with idiopathic pulmonary fibrosis with elastic registration technique on pulmonary three-dimensional ultrashort echo time MRI.

Xiaoyan YangPengxin YuHaishuang SunMei DengAnqi LiuChen LiWenyan MengWenxiu XuBingbing XieJing GengYanhong RenRongguo ZhangXiaopeng LiuHuaping Dai
Published in: Insights into imaging (2024)
• Elastic registration of inspiratory-to-expiratory three-dimensional ultrashort echo time (3D UTE) MRI could evaluate lung deformation. • Lung deformation significantly decreased in idiopathic pulmonary fibrosis (IPF) patients, compared with the healthy controls. • Reduced lung deformation of IPF patients correlated with worsened pulmonary function and the composite physiological index (CPI).
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