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A tri-tuple coordinate system derived for fast and accurate analysis of the colored de Bruijn graph-based pangenomes.

Jindan GuoErli PangHongtao SongKui Lin
Published in: BMC bioinformatics (2021)
Although the solution is made suitable for increasingly complex genome graphs by relaxing the constraint, the directed acyclic graph, the motif cSupB and the cSupB method can be extended to any colored directed acyclic graph. We anticipate that our method will facilitate the analysis of individual haplotype variants and population genomic diversity. We have developed a C +  + program for implementing our method that is available at https://github.com/eggleader/cSupB .
Keyphrases
  • convolutional neural network
  • copy number
  • quality improvement
  • neural network
  • dna methylation
  • mass spectrometry