Do dimethyl fumarate and nicotinic acid elicit common, potentially HCA2 -mediated adverse reactions? A combined epidemiological-experimental approach.
Diana DubrallRené PflockJoanna KosinskaMatthias SchmidMarkus BleichNina HimmerkusStefan OffermannsMarkus SchwaningerBernhardt SachsPublished in: British journal of clinical pharmacology (2021)
The gastrointestinal ADRs common to both substances may be mediated by HCA2 . Other ADRs not common to both substances are compound or indication-specific reactions and likely do not involve HCA2 .