Interleukin-18 as a severity marker and novel potential therapeutic target for epidermolytic ichthyosis.

Osamu AnsaiToshinari MiyauchiRyota HayashiTatsuya KatsumiTomoki NishiguchiAkito HasegawaSatoru ShinkumaKen NatsugaToshifumi NomuraYutaka ShimomuraRiichiro Abe

Published in: Clinical and experimental dermatology (2023)

Our results suggest that serum IL-18 is a severity marker released from the skin of patients with EI. Blockade of IL-18 may be a useful novel therapeutic option for patients with EI.

Keyphrases

soft tissue
human health
risk assessment
climate change