Foxg1 regulates translation of neocortical neuronal genes, including the main NMDA receptor subunit gene, Grin1.

Osvaldo ArtimagnellaElena Sabina MafteiMauro EspositoRemo SangesAntonello Mallamaci

Published in: BMC biology (2024)

These findings point to FOXG1 as a key effector, potentially crucial to multi-scale temporal tuning of neocortical pyramid activity, an issue with profound physiological and neuropathological implications.

Keyphrases

genome wide identification
genome wide
genome wide analysis
copy number
intellectual disability
regulatory t cells
dendritic cells
transcription factor
dna methylation
cerebral ischemia
type iii
bioinformatics analysis
gene expression
brain injury
blood brain barrier