Securely sharing DSMB reports to speed decision making from multiple, concurrent, independent studies of similar treatments in COVID-19.

Natalie A DiltsFrank E HarrellChristopher John LindsellSamuel NwosuThomas G StewartMatthew S ShotwellJill M PulleyTerri L EdwardsEmily Sheffer SerdozKatelyn BenhoffGordon R Bernard

Published in: Journal of clinical and translational science (2022)

It is feasible to coordinate DSMB reviews of multiple independent studies of a similar therapeutic in similar patient cohorts. The materials presented mitigate challenges to DSMBc and will help expand these initiatives so DSMBs may make more informed decisions with all available information.

Keyphrases

decision making
coronavirus disease
sars cov
case control
health information
case report
quality improvement
healthcare
locally advanced
radiation therapy
emergency department