Case Report: Overwhelming Babesia Parasitemia Successfully Treated Promptly With RBC Apheresis and Triple Therapy With Clindamycin, Azithromycin, and Atovaquone.

Yijia LiSusan StanleyJulian A VillalbaSandra NelsonJeffrey Gelfand

Published in: Open forum infectious diseases (2020)

Babesiosis with high-grade parasitemia is life-threatening, especially in asplenic hosts. We report an asplenic patient with parasitemia >50% who was successfully treated with prompt red blood cell apheresis and triple therapy with clindamycin + azithromycin + atovaquone. This regimen may be an alternative to poorly tolerated clindamycin + quinine in severe cases.

Keyphrases

red blood cell
case report
high grade
low grade
early onset
bone marrow
mesenchymal stem cells
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