Establishment and characterization of a HER2-enriched canine mammary cancerous myoepithelial cell line.

Aolei ChenShaotang YeJiahui ZhengJichao LiZejia ChenYashan ZhangShoujun Li

Published in: BMC veterinary research (2023)

A canine cancerous HER2-enriched myoepithelial cell line was successfully established and a canine mammosphere developed from myoepithelial cells was documented in this study. We are expecting this novel cell line and its associated mammospheres could be used as a model to elucidate the role of myoepithelial cells in CMT carcinogensis in the future.

Keyphrases

induced apoptosis
cell cycle arrest
endoplasmic reticulum stress
oxidative stress
signaling pathway
pi k akt