Network-based drug sensitivity prediction.

Khandakar Tanvir AhmedSunho ParkQibing JiangYunku YeuTaeHyun HwangRui Kuang

Published in: BMC medical genomics (2020)

Network-based feature selection method and prediction models improve the performance of the drug response prediction. The relations between the genomic features are more robust and stable compared to the correlation between each individual genomic feature and the drug response in high dimension and low sample size genomic datasets.

Keyphrases

copy number
machine learning
deep learning
adverse drug
drug induced
emergency department
gene expression
dna methylation
single cell