The Human Genetic Differences in the Outcomes of mRNA Vaccination against COVID-19: A Prospective Cohort Study.

Ha-Eun RyuJihyun YoonJa-Eun ChoiSeok-Jae Heo Kyung-Won Hong Dong Hyuk Jung

Published in: Vaccines (2024)

We found that AA genotype holders (rs7795433 SNP of the HDAC9 gene) have a high probability of having a higher antibody count when vaccinated, and GG type holders have a high probability of the opposite. These findings show that the genetic characteristics of vaccinated people may affect antibody production after COVID vaccination.

Keyphrases

genome wide
coronavirus disease
sars cov
copy number
endothelial cells
dna methylation
respiratory syndrome coronavirus
induced pluripotent stem cells
type diabetes
metabolic syndrome
skeletal muscle
insulin resistance
genome wide identification