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Correlation of radiological and histopathological response after neoadjuvant radiotherapy in soft tissue sarcoma.

Sophie J M ReijersNicolò GennaroAnnemarie BruiningHester van BovenPetur SnaebjornssonElise M BekersFrits van CoevordenAstrid N ScholtenYvonne M SchrageWinette T A van der GraafRick L M HaasWinan J van Houdt
Published in: Acta oncologica (Stockholm, Sweden) (2023)
RECIST, Choi and the EORTC-STBSG response score show incongruent results in response evaluation. The radiological response was significantly correlated with a lower percentage of viable cells and necrosis, but a higher percentage of fibrosis. Apart from necrosis, radiological nor other histopathological parameters were associated with oncologic outcomes.
Keyphrases
  • early stage
  • induced apoptosis
  • radiation therapy
  • prostate cancer
  • locally advanced
  • type diabetes
  • radiation induced
  • cell proliferation
  • signaling pathway
  • adipose tissue
  • endoplasmic reticulum stress