GPi-DBS-induced brain metabolic activation in cervical dystonia.

Emma A HonkanenJaana RönkäEero PekkonenJuho AaltonenMaija KoivuOlli EskolaHazem EldebakeyJens VolkmannValtteri KaasinenMartin M ReichJuho Joutsa

Published in: Journal of neurology, neurosurgery, and psychiatry (2023)

GPi-DBS increases metabolic activity at the stimulation site and sensorimotor network. The clinical benefit and adverse effects are mediated by modulation of specific networks.

Keyphrases

deep brain stimulation
resting state
functional connectivity
high glucose
diabetic rats
early onset
white matter
drug induced
endothelial cells
oxidative stress
blood brain barrier
brain injury