α-Synuclein decoy peptide protects mice against α-synuclein-induced memory loss.
Qingyun GuoIchiro KawahataWenbin JiaHaoyang WangAn ChengYasushi YabukiNorifumi ShiodaKohji FukunagaPublished in: CNS neuroscience & therapeutics (2023)
Our findings suggest that the αSyn decoy peptide represents a novel therapeutic approach for reducing the accumulation of toxic αSyn-FABP3 oligomers in the brain, thereby preventing the progression of synucleinopathies.