Impact on Longevity of Genetic Cardiovascular Risk and Lifestyle including Red Meat Consumption.

A Pereira da Silva Maria do Céu CostaLaura AguiarAndreia MatosÂngela GilJ Gorjão-ClaraJorge PolóniaManuel Bicho

Published in: Oxidative medicine and cellular longevity (2020)

Cardiovascular risk-related genetic and multifactorial or predominantly lifestyle aspects and its interactions might influence the aging process and contribute to exceptional longevity in Portuguese centenarians. Besides lifestyle, the activity of nitrite oxide synthase may be one of the main physiologic regulators of cardiovascular protection in the path of longevity.

Keyphrases

metabolic syndrome
weight loss
physical activity
cardiovascular disease
drosophila melanogaster
genome wide
nitric oxide
copy number
transcription factor
type diabetes