Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study.

Andreas BeyerleinEzio BonifacioKendra VehikMarkus HippichChristiane WinklerBrigitte I FrohnertAndrea K SteckWilliam A HagopianJeffrey P KrischerÅke LernmarkMarian J RewersJin-Xiong SheJorma ToppariBeena AkolkarStephen S RichAnette-G Zieglernull null

Published in: Journal of medical genetics (2018)

Genetic risk scores may be used to identify islet autoantibody-positive children with high-risk HLA genotypes who have a slow rate of progression to subsequent stages of autoimmunity and type 1 diabetes.

Keyphrases

type diabetes
glycemic control
genome wide
cardiovascular disease
young adults
copy number
insulin resistance
celiac disease
dna methylation
weight loss