Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation.

Juan D MatuteBenjamin FinanderDavid PepinXingbin AiNeal P SmithJonathan Z LiAndrea G EdlowAlexandra-Chloe VillaniPaul H LerouBrian T Kalish

Published in: Pediatric research (2021)

The implications of maternal SARS-CoV-2 infection in the absence of vertical transmission on fetal and childhood well-being are poorly understood. Maternal SARS-CoV-2 infection might modulate the fetal immune system in the absence of vertical transmission. This study raises important questions about the untoward effects of maternal SARS-CoV-2 on the fetus, even in the absence of vertical transmission.

Keyphrases

birth weight
respiratory syndrome coronavirus
sars cov
pregnancy outcomes
single cell
gestational age
weight gain
preterm infants
high throughput
coronavirus disease
young adults
flow cytometry