Leukocytoclastic vasculitis in patients with IL12B or IL12RB1 deficiency: case report and review of the literature.
Niusha SharifinejadSeyed Alireza MahdavianiMahnaz JameeZahra DaneshmandiAfshin MoniriMajid MarjaniPayam TabarsiParisa FarniaMahsa RekabiMazdak FallahiSeyedeh Atefeh HashemimoghaddamMasoumeh MohkamJacinta BustamanteJean-Laurent CasanovaDavood MansouriAli Akbar VelayatiPublished in: Pediatric rheumatology online journal (2021)
The lack of IL-12 and IL-23 signaling/activity/function and salmonella infection may be triggering factors for the development of leukocytoclastic vasculitis. IL12B or IL12RB1 deficiency and salmonellosis should be considered in MSMD patients with vasculitis.
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