Reduction of Aversive Learning Rates in Pavlovian Conditioning by Angiotensin II Antagonist Losartan: A Randomized Controlled Trial.
Ondrej ZikaJudith AppelCorinna KlingeLorika ShkreliMichael BrowningKatja WiechAndrea Reinecke
Published in: Biological psychiatry (2024)
This study shows that losartan acutely reduces Pavlovian learning in aversive environments, thereby highlighting a potential role of the renin-angiotensin system in anxiety development.