Improved Diagnostics in Bacterial Neonatal Meningitis Using a Next-Generation Sequencing Platform.

Alieke van der Hoeven Martha T van der Beek Vincent BekkerErin MeijersMarco J R IvensEls Wessels Aloysius C M Kroes Stefan A Boers

Published in: Infectious diseases and therapy (2023)

Addition of 16S rRNA sequencing to conventional culturing greatly improved the identification of the aetiology of bacterial meningitis compared to culturing of CSF samples alone.

Keyphrases

cerebrospinal fluid
single cell
high throughput
copy number
gene expression