Neuroprotection in Rats Following Ischaemia-Reperfusion Injury by GLP-1 Analogues-Liraglutide and Semaglutide.

Marina V Basalay Sean M Davidson Derek M Yellon

Published in: Cardiovascular drugs and therapy (2020)

Infarct-limiting and functional neuroprotective effects of liraglutide are dose-dependent. Neuroprotection by semaglutide is at least as strong as by liraglutide and is mediated by GLP-1Rs.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
brain injury
blood brain barrier
acute myocardial infarction
heart failure
acute ischemic stroke
percutaneous coronary intervention
left ventricular
acute coronary syndrome
atrial fibrillation