Single-nuclei RNA Profiling Reveals Disruption of Adipokine and Inflammatory Signaling in Adipose Tissue of Burn Patients.
Carly M KnuthZachary RicciutiDalia BarayanSarah RehouAbdikarim AbdullahiLauar de Brito MonteiroMarc G JeschkePublished in: Annals of surgery (2023)
We provide novel insight towards the effect of burns on adipokine release, inflammatory signaling pathways, and adipose heterogeneity over the trajectory of acute and chronic stages.
Keyphrases
- adipose tissue
- end stage renal disease
- single cell
- insulin resistance
- ejection fraction
- newly diagnosed
- chronic kidney disease
- signaling pathway
- peritoneal dialysis
- oxidative stress
- prognostic factors
- drug induced
- type diabetes
- high fat diet
- intensive care unit
- epithelial mesenchymal transition
- cell proliferation
- extracorporeal membrane oxygenation
- pi k akt