Introducing Savie: A Biodegradable Surfactant Enabling Chemo- and Biocatalysis and Related Reactions in Recyclable Water.
Joseph R A KincaidMadison J WongNnamdi AkporjiFabrice GallouDavid M FialhoBruce H LipshutzPublished in: Journal of the American Chemical Society (2023)
Savie is a biodegradable surfactant derived from vitamin E and polysarcosine (PSar) developed for use in organic synthesis in recyclable water. This includes homogeneous catalysis (including examples employing only ppm levels of catalyst), heterogeneous catalysis, and biocatalytic transformations, including a multistep chemoenzymatic sequence. Use of Savie frequently leads to significantly higher yields than do conventional surfactants, while obviating the need for waste-generating organic solvents.
Keyphrases
- drug delivery
- ionic liquid
- visible light
- photodynamic therapy
- water soluble
- cancer therapy
- room temperature
- heavy metals
- reduced graphene oxide
- highly efficient
- squamous cell carcinoma
- risk assessment
- carbon dioxide
- radiation therapy
- metal organic framework
- amino acid
- gold nanoparticles
- municipal solid waste
- drug induced
- rectal cancer
- life cycle