Informing a target product profile for rapid tests to identify HBV-infected pregnant women with high viral loads: a discrete choice experiment with African healthcare workers.

Yasir Shitu IsaJonathan SicsicHenry NjugunaJohn WardMohamed ChakrounMohamed El-KassasRado RamanampamonjySalim ChalalJeanne Perpétue VincentMonique AnderssonHailemichael DesalegnFatou FallAsgeir JohannessenPhilippa C MatthewsGibril NdowEdith OkekeNicholas RichesMoussa SeydiEdford SinkalaC Wendy SpearmanAlexander StockdaleMichael J VinikoorGilles WandelerRoger SombiéMaud LemoineJudith E MuellerYusuke Shimakawa

Published in: BMC medicine (2023)

African HCWs would prefer an RDT with the following order of priority: higher sensitivity, lower cost, higher specificity, and shorter time-to-result. The development and optimization of RDTs that can meet the criteria are urgently needed to scale up the prevention of HBV mother-to-child transmission in LMICs.

Keyphrases

hepatitis b virus
liver failure
sars cov
mental health
pregnant women
loop mediated isothermal amplification
structural basis
quantum dots
sensitive detection