Angioimmunoblastic T-cell lymphoma after acute myeloid leukemia: Alleged common pathogenesis. A case report and literature review.

Isabel IturrateJavier LoscertalesElena Fernández-RuizPatricia MuñozConsuelo LópezLuciana Del CampoCecilia MuñozAdrián Alegre

Published in: Clinical case reports (2020)

The genomic landscape of AITL is characterized by mutation of epigenetic modifiers. This gene expression pattern resembles myeloid diseases and shows a potential role for hypomethylating agents as possible therapy for AITL.

Keyphrases

acute myeloid leukemia
gene expression
dna methylation
allogeneic hematopoietic stem cell transplantation
copy number
genome wide
bone marrow
acute lymphoblastic leukemia