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Targeting breast cancer with a combination of DNT and LAG3 checkpoint blockage and its mechanism.

Miao WangYuhan WeiYingrui LiHongzhong LiJiangtao JinYuting LuQin Li
Published in: Immunity, inflammation and disease (2022)
Our study revealed the suppressive status of TIME in breast cancer and supported DNT cells had the potential to be applied as a novel adoptive cell therapy for TNBC either alone or combined with LAG3Ab.
Keyphrases
  • cell therapy
  • single cell
  • induced apoptosis
  • dna damage
  • cell cycle arrest
  • cell cycle
  • cancer therapy
  • stem cells
  • endoplasmic reticulum stress
  • drug delivery
  • human health