Hydroxychloroquine in Stage 1 Type 1 Diabetes.

Ingrid M LibmanPolly J BingleyDorothy BeckerJane H Buckner Linda A DiMeglio Stephen E Gitelman Carla J Greenbaum Michael J Haller Heba M IsmailJeffrey KrischerWayne V MooreAntoinette M MoranAndrew B MuirVana RamanAndrea K SteckFrederico G S ToledoJohn M Wentworth Diane K Wherrett Perrin C WhiteLu YouKevan C Heroldnull null

Published in: Diabetes care (2023)

We conclude that hydroxychloroquine does not delay progression to stage 2 T1D in individuals with stage 1 disease. Drug treatment reduces the acquisition of additional autoantibodies and the titers of autoantibodies to GAD and insulin.

Keyphrases

type diabetes
systemic lupus erythematosus
glycemic control
cardiovascular disease
emergency department
metabolic syndrome
adipose tissue
adverse drug
replacement therapy