Genetic polymorphisms of HTR2C, LEP and LEPR on metabolic syndromes in patients treated with atypical antipsychotic drugs.
Apichaya PuangpetchWeerapon UnaharassameeNapa JiratjintanaNapatrupron KoomdeeChonlaphat SukasemPublished in: The Journal of pharmacy and pharmacology (2018)
Therefore, HTR2C genetic variants may be involved in the susceptibility to MS in patients treated with atypical antipsychotics. Additionally, there was a gender effect in the presence of MS. No effect of LEP or LEPR polymorphisms or the combination of HTR2C-LEP and HTR2C-LEPR was observed for the presence of MS.