Differential effects of age at illness onset on verbal memory functions in antipsychotic-naïve schizophrenia patients aged 12-43 years.
Birgitte FagerlundChristos PantelisJens Richardt Moellegaard JepsenJayachandra Mitta RaghavaEgill RostrupMarie Bjerregaard ThomasMette Ødegaard NielsenKirsten Borup BojesenKarsten Gjessing JensenMarie Stentebjerg-DecaraDea Gowers KlauberDitte RudåBjørn H EbdrupKasper JessenAnne SigvardKaren TangmosePia JeppesenChristoph U CorrellAnders Fink-JensenAnne Katrine PagsbergBirte Yding GlenthøjPublished in: Psychological medicine (2020)
Cognitive functions showing protracted maturation into adulthood, such as verbal memory and verbal working memory, may be particularly impaired in both early- and late-schizophrenia onset. Our findings indicate a potential interaction between the timing of neurodevelopmental maturation and a possible premature age effect in late-onset schizophrenia.
Keyphrases
- working memory
- late onset
- bipolar disorder
- transcranial direct current stimulation
- attention deficit hyperactivity disorder
- end stage renal disease
- early onset
- newly diagnosed
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- depressive symptoms
- risk assessment
- climate change
- patient reported
- congenital heart disease