Clinical and biochemical markers of spontaneous preterm birth in singleton and multiple pregnancies.

Sergey V Barinov Gian Carlo Di Renzo Antonina A Belinina Olga V Koliado Olga V Remneva

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2021)

Cervical shortening is the main risk factor of sPTB in women with twin pregnancies; sPTB among singletons is associated with ascendent infection, involving fetal membranes. The PAMG-1 test showed high PPV and NPV for sPTB in symptomatic women and could be a reliable prognostic tool in clinical obstetrics. High NPV was observed for phIGFBP-1 and PAMG-1 in twin pregnancies.

Keyphrases

preterm birth
gestational age
low birth weight
birth weight
risk factors
pregnancy outcomes
polycystic ovary syndrome
metabolic syndrome
body mass index
weight gain
breast cancer risk