Synthesis and Antioxidant Activity of Carane and Pinane Based Sulfenimines and Sulfinimines.

Denis V SudarikovYulia V KrymskayaOksana G ShevchenkoPavel A SlepukhinSvetlana A RubtsovaAleksandr V Kutchin

Published in: Chemistry & biodiversity (2019)

The synthesis of sulfenimines and sulfinimines has been carried out with 10-hydroxyisocamphylthiol. The configuration of the compounds has been deduced by methods of NMR, DFT calculations and X-ray diffraction analysis. The cytotoxic, antioxidant and membrane-protective activity of the synthesized compounds as well as of the previously obtained sulfenimines and sulfinimines based on 4-caranethiol have been determined.

Keyphrases

density functional theory
high resolution
magnetic resonance
oxidative stress
molecular dynamics
molecular dynamics simulations
electron microscopy
anti inflammatory
solid state
computed tomography
contrast enhanced
monte carlo