The humanized platelet glycoprotein VI Fab inhibitor EMA601 protects from arterial thrombosis and ischaemic stroke in mice.

Stefano NavarroIvan TalucciVanessa GöbStefanie HartmannSarah BeckValerie OrthGuido StollHans M MaricDavid StegnerBernhard Nieswandt

Published in: European heart journal (2024)

EMA601 is a conceptually novel and promising anti-platelet agent to efficiently prevent or treat arterial thrombosis and thrombo-inflammatory pathologies in humans at risk.

Keyphrases

pulmonary embolism
oxidative stress
high fat diet induced
monoclonal antibody
metabolic syndrome
insulin resistance
adipose tissue