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Relationship between blood viscosity and no-reflow phenomenon in ST-segment elevation myocardial infarction performed in primary percutaneous coronary interventions.

Arafat YıldırımMehmet KücükosmanogluNermin Yildiz KoyunseverYusuf ÇekiciMehmet Cenk BelibagliAli Nazmi Çalık
Published in: Biomarkers in medicine (2021)
Background: This study aimed to analyze the associations between no-reflow (NR) phenomenon development and whole-blood viscosity in patients with ST-elevated myocardial infarction. Methods: A total of 217 patients with ST-elevated myocardial infarction were included. whole-blood viscosity values were assessed using hematocrit and total protein values, and low shear rate (LSR) and high shear rate (HSR) were calculated. Results: The average LSR and HSR values of the study group were significantly higher than the control group (p < 0.001). Multivariate logistic regression analysis showed that both HSR (odds ratio: 4.957; p < 0.001) and LSR (odds ratio: 1.114; p < 0.001) were independent predictors for NR development. Conclusion: This study found that increased blood viscosity was an independent predictor for NR development.
Keyphrases
  • st segment elevation myocardial infarction
  • heart failure
  • percutaneous coronary intervention
  • left ventricular
  • coronary artery disease
  • coronary artery
  • physical activity
  • small molecule
  • aortic stenosis