Factors Associated with Serious Psychological Distress during the COVID-19 Pandemic in Japan.

Economic situation, caregiving burden, DV, and fear of COVID-19 were independently associated with SPD during the COVID-19 pandemic. Among young women-who have a higher risk of suicide during the COVID-19 pandemic in Japan-similar factors, except economic situation, were associated with a higher rate of SPD. Targeted interventions based on age and gender may be more effective in mitigating the negative impact of the COVID-19 pandemic on the population's mental health.