Prognosis of isolated tumor cells and use of molecular classification in early stage endometrioid endometrial cancer.
Eric V Rios-DoriaNadeem R Abu-RustumKaled M AlektiarVicky MakkerYing L LiuDmitriy ZamarinClaire F FriedmanCarol AghajanianLora H EllensonSarah ChiangBritta WeigeltJennifer J MuellerMario L LeitaoPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2024)
Patients with isolated tumor cells demonstrated less favorable uterine pathologic features and received more adjuvant treatment with similar survival compared with patients with nodenegative disease. Among the available data, molecular classification did not have a significant association with the presence of isolated tumor cells, although copy number-high status was a poor prognostic indicator in early stage endometrioid endometrial cancer.