Low Frequency Of Regulatory B-Cells And Increased CD4+ and CD8+ Interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type.

Yulieth Cristina Bermúdez BurbanoAngie Vanessa Caicedo PazCristhian Camilo Rivera CaldonJuan Sebastián Rodríguez ConstainGloria Inés Ávila GonzálesJulio César Klínger HernándezNancy Marin-AgudeloRosa Amalia Dueñas-CuellarVictoria Eugenia Niño Castaño

Published in: Revista da Sociedade Brasileira de Medicina Tropical (2019)

The low percentage of Breg cells in patients and the increase in the frequency of Th1 cells suggest an imbalance in the control of the inflammatory response that contributes to the immunopathogenesis of TSP/HAM.

Keyphrases

induced apoptosis
cell cycle arrest
inflammatory response
endothelial cells
end stage renal disease
endoplasmic reticulum stress
signaling pathway
oxidative stress
climate change
cell proliferation
peritoneal dialysis
lipopolysaccharide induced
pi k akt