Resistance exercise counteracts the impact of androgen deprivation therapy on muscle characteristics in cancer patients.
Maarten OverkampLisanne H P HoubenThorben AussiekerJanneau M X van KranenburgPhillippe J M PinckaersUlla Ramer MikkelsenMilou BeelenSandra BeijerLuc J C van LoonTim SnijdersPublished in: The Journal of clinical endocrinology and metabolism (2023)
The onset of ADT is followed by a decline in both type I and type II muscle fiber size and capillarization in PCa patients. Resistance exercise training offsets the negative impact of androgen deprivation therapy and increases type I and II muscle fiber size and type I muscle fiber capillarization in these patients.