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Has the introduction of increased genetic prenatal testing affected rates of termination of pregnancy due to fetal abnormality?

Line RaabyStina LouRikke Ramløv Lodberg IvarsenJette SørensenOle Halfdan LarsenIda Vogel
Published in: Prenatal diagnosis (2024)
Unexpectedly, despite the development of new diagnostic tools, the incidence of TOPFA from 2008 to 2021 remained stable. However, the number of cases with genetic aberrations increased. This may be attributed to increased genetic testing for fetuses with identified malformations, resulting in more accurate diagnoses.
Keyphrases
  • copy number
  • genome wide
  • pregnant women
  • preterm birth
  • gene expression
  • dna methylation
  • gestational age