Detection of HIV-1 infections in blood donors during the pre-seroconversion window period in São Paulo, Brazil.
Nanci Alves SallesAnna Shoko NishiyaSuzete Cleusa FerreiraVanderson Geraldo RochaAlfredo Mendrone-JuniorPublished in: Revista da Sociedade Brasileira de Medicina Tropical (2019)
By decreasing the pre-seroconversion window period, nucleic acid testing (NAT) has improved the safety of blood products and reduced the risk of transfusion-transmitted infections. Between 2011 and 2017, NAT determinations for approximately 898,202 donations were performed at Fundação Pró-Sangue/Hemocentro de São Paulo (FPS-HSP). Three seronegative HIV-viremic donations were detected. The NAT yield rate per million donations was 3.34 for HIV, and the acute HIV-1 infections detected are described, followed by a brief review of the situation in Brazil.
Keyphrases
- antiretroviral therapy
- hiv positive
- hiv infected
- hiv testing
- human immunodeficiency virus
- hepatitis c virus
- hiv aids
- men who have sex with men
- nucleic acid
- heat stress
- hepatitis b virus
- oxidative stress
- heat shock
- acute respiratory distress syndrome
- respiratory failure
- quantum dots
- mechanical ventilation
- real time pcr