Parathyroid hormone in surgery-induced weight loss: no glucometabolic effects but potential adaptive response to skeletal loading.
Valeria GuglielmiAlfonso BelliaPaolo GentileschiMauro LombardoMonica D'AdamoDavide LauroPaolo SbracciaPublished in: Endocrine (2017)
Circulating PTH decreases with fat mass reduction independent of 25OHD status, but it is not associated with improvement of insulin resistance and related metabolic parameters. Leptin and PTH may mediate the cross-talk between adipose tissue and parathyroid glands, which possibly contributes to bone adaptation to excess body weight.
Keyphrases
- adipose tissue
- body weight
- insulin resistance
- weight loss
- high fat diet
- minimally invasive
- coronary artery bypass
- bariatric surgery
- high glucose
- bone mineral density
- drug induced
- diabetic rats
- skeletal muscle
- type diabetes
- high fat diet induced
- metabolic syndrome
- roux en y gastric bypass
- soft tissue
- gastric bypass
- human health
- body composition
- bone loss
- bone regeneration
- surgical site infection
- postmenopausal women
- obese patients
- endothelial cells
- atrial fibrillation
- acute coronary syndrome
- risk assessment