Obesity does not modify the effect of continuous positive airway pressure on insulin resistance in adults with obstructive sleep apnoea.
Victoria M PakDavid G MaislinBrendan T KeenanXiaofeng GuoRay TownsendBryndis BenediktsdottirAllan I PackThorarinn GislasonSamuel T KunaPublished in: ERJ open research (2023)
This study found no evidence that obesity significantly modifies the effect of 4 months of CPAP treatment on HOMA-IR. Longer duration of CPAP treatment may be needed in order to reduce insulin resistance and determine whether obesity modifies the effect. https://bit.ly/3CtX7jZ.
Keyphrases
- positive airway pressure
- insulin resistance
- obstructive sleep apnea
- metabolic syndrome
- sleep apnea
- high fat diet induced
- type diabetes
- weight loss
- weight gain
- adipose tissue
- high fat diet
- polycystic ovary syndrome
- skeletal muscle
- escherichia coli
- physical activity
- sleep quality
- combination therapy
- klebsiella pneumoniae
- replacement therapy
- multidrug resistant