Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications.
Arun KumarMirkomil SharipovAbbaskhan TuraevShavkatjon AzizovIsmatdjan AzizovEdwin MakhadoAbbas RahdarDeepak KumarSadanand PandeyPublished in: Polymers (2022)
Globally, cancer is affecting societies and is becoming an important cause of death. Chemotherapy can be highly effective, but it is associated with certain problems, such as undesired targeting and multidrug resistance. The other advanced therapies, such as gene therapy and peptide therapy, do not prove to be effective without a proper delivery medium. Polymer-based hybrid nanoarchitectures have enormous potential in drug delivery. The polymers used in these nanohybrids (NHs)provide them with their distinct properties and also enable the controlled release of the drugs. This review features the recent use of polymers in the preparation of different nanohybrids for cancer therapy published since 2015 in some reputed journals. The polymeric nanohybrids provide an advantage in drug delivery with the controlled and targeted delivery of a payload and the irradiation of cancer by chemotherapeutical and photodynamic therapy.
Keyphrases
- cancer therapy
- drug delivery
- gene therapy
- photodynamic therapy
- papillary thyroid
- reduced graphene oxide
- squamous cell
- drug release
- patient safety
- systematic review
- squamous cell carcinoma
- stem cells
- locally advanced
- cell therapy
- radiation induced
- radiation therapy
- mesenchymal stem cells
- smoking cessation
- bone marrow
- replacement therapy