Local detection of microvessels in IDH-wildtype glioblastoma using relative cerebral blood volume: an imaging marker useful for astrocytoma grade 4 classification.
María Del Mar Álvarez-TorresElies Fuster-GarcíaJavier Juan-AlbarracínGaspar ReynésFernando Aparici-RoblesJaime Ferrer-LozanoJuan Miguel García-GómezPublished in: BMC cancer (2022)
The proposed rCBV marker, calculated from diagnostic MRIs, can detect in IDH-wildtype glioblastoma those regions with microvessels from those without it, and it is significantly correlated with local microvessels area. In addition, the proposed rCBV marker can differentiate the IDH mutation status, providing a complementary non-invasive method for high-grade glioma classification.