Parkinson's Disease Derived Exosomes Aggravate Neuropathology in SNCA*A53T Mice.

Yang HuangZongran LiuNa LiChen TianHan YangYanfei HuoYang LiJing ZhangZhen-Wei Yu

Published in: Annals of neurology (2022)

Novel_miR_44438 in PD-derived L1CAM-purified EVs inhibits the α-syn efflux from neurons thereby promoting the pathological accumulation and aggregation of α-syn. ANN NEUROL 2022;92:230-245.

Keyphrases

cell proliferation
long non coding rna
mesenchymal stem cells
stem cells
spinal cord
high fat diet induced
type diabetes
metabolic syndrome
skeletal muscle
adipose tissue